Where is it being manufactured?
While there are some doses coming from Europe in the very first instance, the majority will be provided from the UK supply chain.
Do you need two doses of the Oxford vaccine?
The MHRA has recommended the over 18s should receive two doses to be administered with an interval of between four and 12 weeks.
Can this vaccine help the elderly?
There have been concerns that a Covid-19 vaccine will not work as well on elderly people, much like the annual flu jab.
However, data from the Oxford/AstraZeneca trial suggests there have been “similar” immune responses among younger and older adults.
The results show that the vaccine is better tolerated in older people compared with younger adults, and produces a similar immune response in old and young adults.
Can pregnant women have the vaccine?
Pregnant women and breastfeeding mothers have now been given the green light to take either the Oxford and Pfizer coronavirus vaccines following an appropriate case-by-case risk evaluation with their healthcare practitioner.
This is a reversal of previous advice which was put in place as precautionary measure.
Traditionally pregnant women are not included in clinical trials, but following a review the MHRA are recommending pregnant women be given the opportunity to receive the vaccine as as there is no evidence they would be at risk.
Dr June Raine, chief executive of the MHRA, said: “Our advice to date has been that given that in initial lack of evidence on a precautionary basis, use of a vaccine wasn’t recommended in pregnancy and women with breastfeeding should not be given the vaccine.
“But now that we have reviewed further data that has become available, the Commission on Human medicines has advised that the vaccine can be considered for use in pregnancy when the potential benefits outweigh the risks following an individual discussion with every woman.”
Can people with allergies have the vaccine?
The roll-out of the Pfizer vaccine was halted for those who are known to suffer from severe allergic reactions following a handful of adverse events in the initial distribution of the vaccine.
There were some concerns that this would also apply to the Oxford jab.
However, following a review, the UK regulatory body has recommended both the Pfizer and Oxford vaccine are safe to administer to those with food or medicine allergies.
Only those who have a known history of reacting to vaccines in the past should proceed with caution.
Sir Munir Pirmohamed, clinical pharmacologist and geneticist, and chairman of Commission on Human Medicine Expert Working Group, said. “We’ve come to the recommendation people with a known history of reacting to any specific ingredients of vaccine should not have it. But people with allergies to other medicines or food can have the vaccine.”
Dr June Raine added that “at least 800,000 in the UK, probably a million and a half in the US” have already received the Pfizer vaccine.
There has been “no additional concerns and this gives us further assurance that the risk of anaphylaxis can be managed through standard clinical guidance and an observation period following vaccination of at least 15 minutes.”
When will roll-out of the Oxford vaccine start?
The Oxford vaccine will be rolled out from January 4 across the country under plans being drawn up by ministers, The Telegraph can reveal.
The Government is aiming for two million people to receive their first dose of either the Oxford vaccine or the Pfizer jab within a fortnight as part of a major ramping up of the inoculation programme.
The Telegraph can also disclose that mass vaccination centres at sports stadiums and conference venues are primed to launch in the second week of January.
An army of more than 10,000 medics and volunteers has been recruited by the NHS to help deliver the Oxford Covid-19 vaccine.